In this module you will develop an understanding of the five Kingdoms of living organisms. You will look at the basic principles of evolution and natural selection and why these are important for zoological and botantical classification. You will examine the links between functional anatomy and evolutionary development, and assess broader concepts of biodiversity. You will learn techniques in the handling and observation of preserved and live specimens, preparation of taxonomic keys, drawing, data analysis and presentation.
In this module you will develop an understanding of the principles of ecology and conservation, and examine how these influence animal behaviour. You will look at how organisms adapt to key UK habitats, and the challenges of living in such environments. You will also assess the methods used for studying ecological systems, becoming familiar with common sampling techniques and how to apply and interpret common statistical tests.
In this module you will develop an understanding of the fundamental physiological processes required for communication, obtaining and distributing nutrients, and maintaining the internal environment within multicellular organisms. You will look at how changes in internal and external environments are assessed by animals and plants, and examine the ways in which plants and animals obtain oxygen, carbon dioxide, water and energy, and rid themselves of waste materials. You will also consider the key properties of organ systems which support mobility.
In this module you will develop an understanding of the basic features of microbes and the diversity of microorganisms. You will look at the subcellular features of prokaryotic and eukaryotic cells, examining the key functions of these structures and organelles. You will consider celluar genetics with respect to mitosis, meiosis, inheritance and recombination, and the fundamentals of genome organisation, transcription and translation. You will also learn practical techniques in microscopy, including slide prepration for the observation of chromosomes, and fixation techniques for the analysis of cell ultrastructure.
In this module you will develop an understanding of invertebrate phyla, looking at their structure, diversity, levels of complexity, life styles, and evolutionary relationships. You will primarily examine body-plans and how structure relates to behaviour, but also consider invertebrate diversity and their ecological importance. You will learn to stain, mount, and interpret microscopic specimens and enhance your skills in scientific illustration, microscope use, identification and animal handling.
In this module you will develop an understanding of the life cycle of flowering plants, considering their evolution, developmental and functional biology. You will examine the role and biology of meristems in the structure and building of a plant muticellular body, and the role and mode of action of plant hormones in coordinating development. You will also consider a range of environmental and biotic factors affecting plants, including light, time of day, temperature, drought, and other organism, and how plants respond to the challenges they pose.
In this module you will develop an understanding of the use of statistical methods in biological sciences. You will examine how questions in biology can be answered using quantitative methods, looking at key concepts of statistical sampling and experimental design. You will consider how to select appropriate tests, how to apply them, and identify what can be deduced from them.
In this module you will develop an understanding of the molecular tools and techniques currently available to investigate the genetic diversity of a range of organisms. You will examine how genetically modified organisms can be produced via a number of methodologies, and will consider their application in areas such as crop improvement, pest management, and vaccine development. You will also look at how molecular genetics has improved our understanding of human inherited diseases, and led to development of human gene therapies.
In this module you will develop an understanding of how organisms have changed through time. You will look at the historical origins of the modern concept of evolution, examinining the evidence for it and the processes that have shaped faunas and floras. You will consider Darwinism and its development, the origin and maintenance of variation, and adaptation and selection. You will analyse how evolution can be studied using phylogenetic methods and the mechanisms of speciation, with a focus on human evolution.
You will carry out an individual laboratory or theoretical investigation, supervised by an appropriate member of staff, who will provide guidance throughout. You will apply the knowledge and skills learned throughout your studies, and learn to organise data in a logical, presentable and persuasive way. You will produce a report, around 8,000 words in length, and will deliver an oral presentation with a summary of your findings.
In this module you will develop an understanding of the principles of parasitism and the protective mechanisms used by immuno-competent hosts to limit the spread of infection. You will look at the biological strategies used by a range of unicellular and multicellular organisms to colonise host causing disease in human and non-human hosts. You will consider studies on the pathology and the cellular immunity elicited by various parasites, and the immune evasion strategies used by widely distributed human parasites to protect themselves from immune attack. You will also address the principles and prospects of anti-parasitic vaccination in the 21stCentury.
In this module you will develop an understanding of the effects of climate change on the interaction between plants and the environment. You will critically evaluate the application of novel technologies to crop improvement, and assess the relationship between growth and reponses to the environment. You will also consider issues surrounding human uses of plants and conservation.
In addition to these mandatory course units there are a number of optional course units available during your degree studies. The following is a selection of optional course units that are likely to be available. Please note that although the College will keep changes to a minimum, new units may be offered or existing units may be withdrawn, for example, in response to a change in staff. Applicants will be informed if any significant changes need to be made.
Only core modules are taken
In this moudle you will develop an understanding of the physical and chemical characteristics of the marine environmental and their influence on marine organisms. You will look at of a broad range of marine taxa, in particular invertebrates, but also vertebrates and algae, sampled alive from their natural habitats. You will carry out intertidal sampling (rocky and sandy shores) and sampling from a research vessel (plankton and subtidal benthos), gaining experience of collecting and identifying a range of littoral organisms. You will consider behavioural, ecological and physiological aspects, morphological adaptations, systematic relationships and also the economic significance of selected groups.
In this module you will develop an understanding of some of the key concepts in microbiology, including the study of bacteria, viruses, and eukaryotic microbes. You will look at how microbes are distinguished and classified, and discuss bacterial growth and differentiation. You will examine the importance of microorganisms in health and disease, including human welfare issues such as opportunistic infections and the role of microorganisms in cancer.
In this module you will develop an understanding of the key methologies used in cell biology, becoming familar with modern microscopy techniques and live cell imaging studies. You will look at the basic mechanisms that regulate the cell cycle and the regulatory mechanisms for DNA synthesis and mitosis. You will examine mitochondria and chlorpolast organelle functions, and the principles of polar bodies and asymmetric cell division. You will assess the basic mechanisms underlying cell shape and mobility, and consider the evolutionary constrains of cellular functions.
Essential Human Physiology in Health and Disease
In this module you will develop an understanding of the function and integration of selected human physiological systems in normal physiology and disease. You will look at endocrine control in the human body, specifically the role of the hypothalamo-pituitary axis and the function and regulation of thyroid hormones. You will examine the organisation and integration of the nervous, cardiovascular, respiratory and systems and the principles of whole muscle physiology. You will also consider the composition and functions of blood and haemostasis, and the the analysis and interpretation of physiological experiments.
In this module you will develop an understanding of the processes that lead from a fertilised egg into complex tissues and organisms with well-defined body plans. You will look at the basic cellular and genetic mechanisms that regulate development, and the evolutionary outcomes of developmental changes. You will examine model organisms in which both embryological and genetic approaches have been developed, and will explore axis establishment, segmentation, cellular differentiation, organ development, and the widely-shared signalling pathways that underpin them.
Insects, Plants and Fungi - Ecology and Applications
In this module you will develop an understanding of the effects of herbivorous insects on plants and the ways in which plants defend themselves against attack. You will consider how insects can be beneficial to plants, examining their role in pollination, and how fungi mediate interactions between insects and their hosts, including pathogens, endophytes and mycorrhizas.
Practical Field Ecology
In this module you will develop an understanding of how to design and analyse ecological experiments. You will perform simple investigations into several different taxonomic groups such as mammals, invertebrates and plants, and consider the difficulties of designing experiments in the field, compared to controlled conditions. You will gain experience with techniques such as field sampling, identification using keys, and quantitative population estimation, as you carry out fieldwork in and around the College campus, with some daily excursions.
In this module you will develop an understanding of the causation, development, function and evolution of animal behaviour, assessing the variety of behaviour occurring across the range of animal taxa and in different ecological situations. You will examine the major theories that seek to explain animal behaviour, such as kin selection, optimal foraging and game theory. You will look at the main methods used to study behaviour, including observation, experiment and the comparative approach, and consider how they can be applied to the study of different types of behavioural questions.
In this module you will develop an understanding of the chemical structure of DNA and RNA, and how genes are organised and expressed. You will look at gene characterisation using recombinant DNA technology, and will consider DNA as a template for RNA synthesis. You will also become familiar with molecular biology techiques that are widely used in the life sciences, including the preparation and handling of purified DNA, restriction enzyme digestions, and polymerase chain reaction.
Molecular and Cellular Immunology
In this module you will develop an understanding of the mammalian immune systems at cellular and molecular levels, and how this is determined by antibody structure and function, the complement system, and the impact of immunoglobulin genetics. You will look at the role of T cells as effectors and regulators of immune responses, allergic reactions, transplant rejection, and the HIV virus and the pathogenesis of AIDS on the immune system. You will examine antipody antigen reaction techniques used in immunology, and consider the isolation and purification of lymphocytes, their morphology and abundance.
In this module you will develop and understanding of the major threats to biodiversity, including habitat loss and fragmentation, alien species, global climate change, intensive agriculture, pollution, and over-harvesting. You will look at the population and ecological processes that lead to species and habitat decline, and assess how conservation biology can be applied to redress this. You will also examine current areas of research in conservation biology, their ethical implications, and agri-environmental management plans.
Entomology - Pure and Applied
In this module you will develop an understanding of insect biology, addressing aspects of their physiology and biology. You will look at why insects are the most numerous animals on the planet and examine the practical applications of entomology. You will assess modern methods of crop production and pest control, and will analyse the conservational importance of beneficial insects such as pollinators and saproxylic (dead wood feeding) species, considering reasons for their decline.
Mediterranean Island Conservation and Ecology
In this module you will develop an understanding of the ecology of the Alentejo region of Portugal, and the conservation threats presented by tourism, infrastructure development and agricultural change. You will look at conservation ecology in marine, aquatic and terrestrial ecosystems, with a focus on key species and habitats. You will carry out practical work, including an ecological risk assessment for coastal ecosystems, invertebrate sampling in native cork forest, bird monitoring, river-based surveys for invasive crayfish and otters, marine surveys, pollinator surveys on invasive plants, and kayak-based surveys for aquatic infauna.
Population and Community Ecology
In this module you will develop an understanding of the principles of population and community ecology, focussing on the forcs which structure communities of animals and plants. You will look at population growth, inter- and intra-specific competition, trophic relations and the factors which regulate populations, and will examine the ecological processes that contribute to community organisation, such as food web structure, body size, succession and natural disturbances. You will also consider the role of population and community ecology in the maintenance of biodiversity.
In this module you will develop an understanding of how ecologists investigate the behaviour of animals, looking at recent advances in behavioural ecology research. You will analyse the functional and evolutionary hypotheses that seek to explain how animals find and use key resources, such as food, breeding territories and mates, and consider how simple models, such as game theory, can be used to test these.
Marine Ecology and Biodiversity
In this module you will develop an understanding of the diversity habitats in the marine environment and the range of responses seen in marine biota. You will look at the diversity of organisms, considering the key processes operating in coral reefs, the deep ocean and hydrothermal vent systems. You will consider the behaviour and conservation of marine species, the impact of marine pollution and climate change on marine biodiversity, and examine the adaptation of mammals to marine life.
Molecular and Medical Microbiology
In this module you will develop an understanding of medical microbiology with particular reference to bacteria and pathogenic eukaryotes. You will look at pathogen mechanisms for infection, the host immune response to infection, vaccine development, gastrointestinal health and disease, resistance to antibiotics, anti-parasite chemotherapy and the genetic and biochemical validation of parasite drug targets in the kinetoplastidae. You will examine the role of probiotics in health and disease, and consider a range of microbiological and molecular diagnostics techniques.
Seed Biology - Molecular and Conservation Biology to Industrial Applications
In this module you will develop an understanding of the importance of seeds and fruits for food chain security, the seed industry, and ecosystem conservation. You will look at the principles and importance of seed banking and the seed conservation work at Kew's Millenium Seed Bank to mitigate against climate change. You will examine the developmental and biochemical processes of seed storage reserve deposition, germination and reserve mobilisation, including the environmental control of seed germinsation. You will analyse the key advantages of the seed habit, considering the morphological diversity of modern seeds and fruits which have evolved.
Applications of Advanced Molecular Biology Methods
In this module you will develop an understanding of the transformation technologies used in the study of gene expression, gene therapy and biotechnological applications of genetically modified organisms. You will consider how molecular biology research is employed in a range of systems, including animal and plant models, as well as the simple social amoeba, Dictyostelium. You will also analyse the use of molecular genetics in the study of circadian rhythms.
Cell and Molecular Biology of Cancer
In this module you will develop an understanding of advanced concepts and recent advances in fundamentally important areas of cell biology revelant to cancer, including developments in microscopy, imaging and molecular genetic techniques. You will look at current concepts in molecular cell biology, such as cell-cell adhesion and signalling, stem cells in development and in diseases, and cancer and the role of the cytoskeleton. You will examine topics in cancer biology including oncogenes, tumour suppressor genes and caretaker genes, and the signalling and regulatory pathways these are involved in. You will also examine the diagnosis and rational of cancer therapies.
Human Embryology and Endocrinology
In this module you will develop an understanding of human embryos and the development and function of particular endocrine systems. You will look at embryonic development, including gastrulation and specification of the axes, and the initial steps in the formation and patterning of the brain and spinal cord. You will examine craniofacial development, pharyngeal gland formation and sex determination, analysing the cellular and molecular processes involved in detail. You will also consider some of the birth defects that can arise, the genetic and environmental insults that cause them, and investigations which inform their prevention.
Special Study - Dissertation
You will carry out a literature research project on a biological or biochemical topic of your choice, producing a written report around 7,500 words in length. You will critically evaluate recent scientific literature on your chosen topic, highlighting how data has been used to generate and test hypotheses.