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More in this section Research

Publications

Selected publications from the Institute

publications

A number of publications have been produced by members of the Institute of Cardiovascular Research. You can find out more about each one, including its authors, in each box.

Read an overview of our research here

Shared genetic basis for migraine and ischemic stroke

Article title :  Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants.  

Publication:   Neurology 2015 (in press).

Authors: R ainer Malik, Tobias Freilinger, Bendik S Winsvold, Verneri Anttila, Jason Vander Heiden, Matthew Traylor, Boukje de Vries, Elizabeth G Holliday, Gisela M Terwindt, Jonathan Sturm, Joshua C Bis, Jemma C Hopewell, Michel D Ferrari, Kristiina Rannikmae, Maija Wessman, Mikko Kallela, Christian Kubisch, Myriam Fornage, James F Meschia, Terho  Lehtimäki, Cathie Sudlow, Robert Clarke, Dan I Chasman, Braxton D Mitchell, Jane Maguire, Jaakko Kaprio, Martin Farrall, Olli T Raitakari, Tobias Kurth, M Arfan Ikram, Alex P Reiner, W T Longstreth Jr, Peter M Rothwell, David P Strachan, Pankaj Sharma, Sudha Seshadri , Lydia Quaye,  Lynn Cherkas , Markus Schürks, Jonathan Rosand, Lannie Ligthart, Giorgio B Boncoraglio, George Davey Smith, Cornelia M van Duijn, Kari Stefansson, Bradford B Worrall, Dale R Nyholt, Hugh S Markus, Arn MJM van den Maagdenberg, Chris Cotsapas, John A Zwart, Aarno Palotie, Martin Dichgans.  

Genetic overlap between diagnostic subtypes of ischemic stroke

Article title: Genetic overlap between diagnostic subtypes of ischemic stroke.

Publication: Stroke 2015 (in press).

Authors: Holliday E et all (incl Sharma P).

Common variation in PHACTR1

Article title: Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection.

Publication: Nat Genet 2014 (in press).

Authors: Debette S, et al (incl Sharma P).

Common variation in COL4A1/COL4A2

Article title: Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease.

Publication: Neurology 2014 (in press).

Authors: Kristiina Rannikmäe, Gail Davies, Pippa A Thomson, Steve Bevan, William J Devan, Guido J Falcone, Matthew Traylor, Christopher D Anderson, Thomas WK Battey, Farid Radmanesh, Ranjan Deka, Jessica G Woo, Lisa J Martin, Jordi Jimenez-Conde, Magdy Selim, Devin L Brown, Scott L Silliman, Chelsea S Kidwell, Joan Montaner, Carl D Langefeld, Agnieszka Slowik, Björn M Hansen, Arne G. Lindgren, James F. Meschia, Myriam Fornage, Joshua C Bis, Stéphanie Anne-Carine Debette, Mohammad Arfan Ikram, Will T Longstreth, Reinhold Schmidt, Cathy Zhang, Qiong Yang, Pankaj Sharma, Steven Kittner, Braxton D. Mitchell, Elizabeth G Holliday, Christopher Royce Levi, John Attia, Peter M Rothwell, Deborah L Poole, Giorgio B Boncoraglio, Bruce M Psaty, Rainer Malik, Natalia S. Rost, Bradford B. Worrall, Martin Dichgans, Tom Van Agtmael, Daniel Woo, Hugh S Markus, Sudha Seshadri, Jonathan Rosand, and Cathie L.M. 

Effect of genetic variants .... on stroke risk

Article title: Effect of genetic variants associated with plasma homocysteine levels on stroke risk. 

Publication: Stroke 2014; 45:1920-4.

Authors: Ioana Cotlarciuc, Rainer Malik, Elizabeth G. Holliday, Kourosh R Ahmadi, Guillaume Pare, Bruce M. Patsy, Myriam Fornage, Nazeeha Hasan, Paul E. Rinne, M. Arfan Ikram, Hugh S Markus, Jonathan Rosand, Braxton D. Mitchell, Steven J. Kittner, James F. Meschia, Joyce BJ van Meurs, Andre G Uitterlinden, Bradford B. Worrall, Martin Dichgans, Pankaj Sharma.

Etiologic Ischemic Stroke Phenotypes in the NINDS Stroke Genetics Network

Article title: Etiologic Ischemic Stroke Phenotypes in the NINDS Stroke Genetics Network.

Publication: Stroke 2014 (in press).

Authors: Hakan Ay, Ethem Arsava, Gunnar Andsberg, Thomas Benner, Robert Brown, Sherita Chapman Smith, John Cole, Hossein Delavaran, Martin Dichgans, Gunnar Engström, Eva Giralt-Steinhauer, Raji Grewal, Katrina Gwinn, Christina Jern, Jordi Jimenez-Conde, Katarina Jood, Michael Katsnelson, Brett Kissela, Steven Kittner, Dawn Kleindorfer, Daniel Labovitz, Silvia Lanfranconi, Jin-Moo Lee, Manuel Lehm, Robin Lemmens, Christopher Levi, Linxin Li, Arne Lindgren, Hugh Markus, Patrick McArdle, Olle Melander, Bo Norrving, Leema Reddy Peddareddygari, Annie Pedersen, Joanna Pera, Kristiina Rannikmäe, Kathryn Rexrode, J Rhodes, Stephen Rich, Jaume Roquer, Jonathan Rosand, Peter Rothwell, Tatjana Rundek, Ralph Sacco, Reinhold Schmidt, Markus Schürks, Stephan Seiler, Pankaj Sharma, Agnieszka Slowik, Cathie Sudlow, Vincent N Thijs, Rebecca Woodfield, Bradford Worrall, James Meschia.

Agreement between TOAST and CCS ischemic stroke classification

Article title: Agreement between TOAST and CCS ischemic stroke classification in a large multi-centered study: The NINDS SiGN Study.

Publication: Neurology 2014 (in press).

Authors: Patrick F McArdle, Steven J Kittner, Hakan Ay, Robert D Brown, Jr., James F Meschia, Tatjana Rundek, Sylvia Wassertheil-Smoller, Daniel Woo, Gunnar Andsberg, Alessandro Biffi, David A Brenner, John W Cole, Roderick Corriveau, Paul I.W. de Bakker, Hossein Delavaran, Martin Dichgans, Raji P. Grewal, Katrina Gwinn, Mohammed Huq, Christina Jern, Jordi Jimenez-Conde, Katarina Jood, Robert C Kaplan, Petra Katschnig, Michael Katsnelson, Daniel L Labovitz, Robin Lemmens, Linxin Li, Arne Lindgren, Hugh S Markus, Leema Reddy Peddareddygari, Annie Pedersen, Joanna Pera, Petra Redfors, Jaume Roquer, Jonathan Rosand, Natalia S Rost, Peter M Rothwell, Ralph L Sacco, Pankaj Sharma, Agnieszka Slowik, Cathie Sudlow, Vincent Thijs, Steffen Tiedt, Raffaella Valenti, and Bradford B Worrall.

Increased platelet expression of glycoprotein IIIa

Article title: Increased platelet expression of glycoprotein IIIa following aspirin treatment in aspirin-resistant but not aspirin-sensitive subjects.

Publication:  Brit J Clin Pharm 2014 (in press).

Authors: Christopher Floyd, Timothy Goodman, Silke Becker, Nan Chen, Agnesa Mustafa, Emma Schofield, James Campbell, Malcolm Ward, Pankaj Sharma, Albert Ferro.

A novel MMP12 locus is associated with large artery atherosclerotic stroke

Article title:  A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach.

Publication: PLoS Genetics 2014 (in press).

Authors: Matthew Traylor, MSc; Kari-Matti Makela; Laura Kilarski; Elizabeth G Holliday; William J Devan; Mike A Nalls; Kerri L Wiggins; Wei Zhao; Yu-Ching Cheng; Sefanja Achterberg; Rainer Malik; Cathie Sudlow; Steve Bevan; Emma Raitoharju; Niku Oksala; Vincent Thijs; Robin Lemmens; Arne Lindgren; Agniesczka Slowik; Jane M Maguire; Matthew Walters; Ale Algra; Pankaj Sharma; John R Attia; Giorgio B Boncoraglio; Peter M Rothwell; Paul I W Bakker; Joshua C Bis; Danish Saleheen; Steven J Kittner; Braxton D Mitchell; Jonathan Rosand; James F Meschia; Christopher Levi; Martin Dichgans; Terho Lehtimaki; Cathryn Lewis; Hugh Markus.

Lesion locations influencing baseline severity in ischemic stroke

Article title: Lesion locations influencing baseline severity and early recovery in ischemic stroke.

Publication: Euro J Neurol 2014 (in press).

Authors: Bentley, P.; Kumar, Guru; Rinne, Paul; Buddha, Sandeep; Kallingal, Jouher; Hookway, Cheryl; Sharma, Pankaj; Mehta, Amrish; Beckmann, Christian.

Multilocus genetic risk score associates with ischemic stroke

Article title: Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies.

Publication: Stroke 2014;45:394-402.

Authors: Malik R, Bevan S, Nalls MA, Holliday EG, Devan WJ, Cheng YC, Ibrahim-Verbaas CA, Verhaaren BF, Bis JC, Joon AY, de Stefano AL, Fornage M, Psaty BM, Ikram MA, Launer LJ, van Duijn CM, Sharma P, Mitchell BD, Rosand J, Meschia JF, Levi C, Rothwell PM, Sudlow C, Markus HS, Seshadri S, Dichgans M; Wellcome Trust Case Control Consortium 2.

Meta-analysis in over 17,900 cases of ischemic stroke reveals a novel association

Article title: Meta-analysis in over 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.

Publication: Neurology 2014;83:678-85.

Authors: Laura L Kilarski, Sefanja Achterberg, William Devan, Matthew Traylor, Rainer Malik, Arne Lindgren, Guillame Pare, Pankaj Sharma, Agnieszka Slowik, Vincent N. Thijs, Matthew Walters, Bradford B Worrall, Michele Sale, Ale Algra, Jaap Kappelle, Cisca Wijmenga, Bo Norrving, Johanna Sandling, Lars Ronnblom, An Goris, Andre Franke, Cathie Sudlow, Peter M Rothwell, Christopher Levi, Elizabeth G Holliday, Myriam Fornage, Bruce Psaty, Solveig Gretarsdottir, Unnar Thorsteindottir, Sudha Seshadri, Braxton Mitchell, Steven Kittner, Robert Clarke, Jemma Hopewell, Joshua Bis, Giorgio Boncoraglio, James Meschia, Arfan Ikram, Bjorn Hansen, Joan Montaner, Gudmar Thorleifsson, Kari Stefanson, Jonathan Rosand, Paul I W de Bakker, Martin Farrall, Martin Dichgans, Hugh S Markus, and Steve Bevan.

Prediction of stroke thrombolysis outcome using CT brain machine

Article title: Prediction of stroke thrombolysis outcome using CT brain machine learning.

Publication: Neuroimage 2014; 4; 635-640.

Authors: Paul Bentley, Jeban Ganesalingam, Anomas Dias, Kate Mahady, Sarah Epton, Paul Rinne, Pankaj Sharma, Omid Halse, Amrish Mehta, Daniel Rueckert.

Knowledge of blood pressure in a UK general public population

Article title:  Knowledge of blood pressure in a UK general public population.

Publication: J Hum Hypertens 2014 (in press).

Auithors: Slark J, Khan MS, Bentley P, Sharma P.

Shared genetic susceptibility to ischemic stroke and coronary artery disease

Article title: Shared genetic susceptibility to ischemic stroke and coronary artery disease - a genome-wide analysis of common variants.

Publication: Stroke 2014 (in press).

Authors: Dichgans M, Malik R, König IR, Rosand J, Clarke R, Gretarsdottir S, Thorleifsson G, Mitchell BD, Assimes TL, Levi C, Odonnell CJ, Fornage M, Thorsteinsdottir U, Psaty BM, Hengstenberg C, Seshadri S, Erdmann J, Bis JC, Peters A, Boncoraglio GB, März W, Meschia JF, Kathiresan S, Ikram MA, McPherson R, Stefansson K, Sudlow C, Reilly MP, Thompson JR, Sharma P, Hopewell JC, Chambers JC, Watkins H, Rothwell PM, Roberts R, Markus HS, Samani NJ, Farrall M, Schunkert H.

Article title:

Contributions of maternal and paternal adiposity and smoking to adult offspring adiposity and cardiovascular risk: the Midspan Family Study

Han TS Contributions of maternal and paternal adiposity and smoking to adult offspring adiposity 

 
 
 

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