School of Biological Sciences Seminar Series
Lecturer, Royal Veterinary college
Understanding mechanisms and searching or cures for neurodegeneration and epilepsy: how useful is the zebrafish?
Abstract: Zebrafish are particularly suited to mechanistic studies and drug discovery and Claire Russell is developing zebrafish disease models, predominantly focussing on epilepsy and neurodegeneration in order to support efforts to understand disease and search for novel therapies for these devastating disorders. Claire will present the validation of two novel zebrafish disease models: Epilepsy, Ataxia, Sensorineural deafness and Tubulopathy (EAST) syndrome and late infantile neuronal ceroid lipofuscinosis (LINCL; CLN2 disease) and illustrate the use of these and other zebrafish models for drug discovery and mechanistic studies.
Host Professor Robin Williams